ELSEVIER Biochemical applied science Journal 2 ( 1998) Biochemical Engineering Journal 1 l-21 A structured seat for penicillin meshment on mixed substrates G.C. Paul, M.T. Syddall, C.A. Kent, C.R. Thomas * Centre for Bioprocess Engineering, domesticate of chemical Received Engineering, 23 January The University of Birmingham, 1998; accepted 7 May Edgbaston, Birmingham, B15 2lT, UK 1998 summary A structured energising modelpreviouslydeveloped describe growth,differentiation, penicillinproduction Penicillium chryysoto the and of genum has been compound andextended orderto apply it to a mixedcarbonsource fermentation. filamentous in The hyphae dividedinto are quartet distinctregions thebasis theiractivitiesandthephysiological on of structure (i.e., vacuolation)of thehyphalcompartments: actively viz., growing(mainly apical)regions, non-growing penicillinproducing or regions, vacuoles, degenerated metabolically and or inactiveregions. A simpleapproach takento give quantitative is descriptions hyphal extension, of branchformation,vacuolation differentiation.The and fermentation medium contained lucose andlactose g monohydrate the maincarbonsources.
The source the lactose whey powder as of was employ in excess in theinoculum medium, whilstglucose fedcontinuously was throughout fermentation. the Lactose,disaccharide, is hydrolysed a to twain monosaccharides, glucose and gaiactose, when the rest period glucose concentration in the medium drops to a very gloomy level. The utilisation of glucose that of galactose and following! the hydrolysisof lactosewereobserved occursimultaneously. allowedthe to This assumption simplelactoseutilisationkineticsin which lactosehydrolysiscould be considered producingan equivalentamountof of as glucose. model been sed for successful The has u predictions fed-batch of penicillinfermentations usinganindustrial chyogenum strain P. under...If you indigence to tick a full essay, order it on our website:
BestEssayCheap.comIf you want to get a full essay, visit our page:
cheap essay
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.